Drawing a map of genes might help us predict who will get sick and when we will get sick of heart disease or cancer. And we have seen Angelina Jolie, the famous actress, going for a preventive mastectomy because she had a faulty gene for breast cancer. But Is it the inevitable destiny, or can we change it? Do genes decide who will have heart disease? Who is to be blamed for heart disease? The genes we inherit, or the environment where we grow and live?Can your good genes protect you from your unhealthy lifestyle? Can a good lifestyle buffer our faulty genes?Watch it 🎦 on YouTube Read 📖it on LinkedIn ReferencesCirculation. 2022;145:808–818. DOI: 10.1161/CIRCULATIONAHA.121.053730https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.121.053730