The Charlotte Greenwood Show is a radio situation comedy in the United States. It was broadcast on NBC from June 13 to September 5, 1944, and on ABC from October 15, 1944, to January 6, 1946.

The program began as a summer replacement for The Bob Hope Show. Newspaper columnist Hedda Hopper reported, "The interesting thing is that she (Charlotte Greenwood) got the job on a couple of scripts written by her husband, Martin Broones, who's never before written for radio."