Duffy's Tavern is an American radio situation comedy that ran for a decade on several networks (CBS, 1941–42; NBC-Blue Network, 1942–44; and NBC, 1944–51), concluding with the December 28, 1951, broadcast.

The program often featured celebrity guest stars but always hooked them around the misadventures of Archie, the tavern's manager, portrayed by Ed Gardner. Archie was prone to involvement in get-rich-quick schemes and romantic missteps, and constantly communicated with malaprops and mixed metaphors. Gardner had performed the character of Archie, talking about Duffy's Tavern, as early as November 9, 1939, when he appeared on NBC's Good News of 1940