CAPS, also known as Asherson’s Syndrome, represents less than 1% of all APS cases but is widely recognized as its most severe clinical manifestation, with a mortality rate of 30–50% despite treatment. mortality rate of 30–50% despite treatment. Unlike classical APS, which usually involves isolated thrombosis or pregnancy morbidity, this form is characterized by rapidly progressive, simultaneous or sequential thromboses, frequently leading to multiorgan failure.

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