Welcome back to episode 2. In this episode I explain the difference between IgE-mediated food allergy, non IgE mediated food allergy and mixed IgE and non IgE food allergy and I also talk about the immune mechanism that underlies an allergic reaction and what the methods are to diagnosing food allergy with a specific focus on IgE-mediated food allergy in this episode. I also share stories along the way of my personal experiences. If you would like to find out more please do visit my blog post which will detail everything that was discussed in the podcast. You can find the blog post based on this podcast on my website under blogs.

Reference list:
Aziz, M., Iheanacho, F. and Hashmi, M.F., 2019. Physiology, Antibody.

Nicholson, L.B., 2016. The immune system. Essays in biochemistry, 60(3), pp.275-301

Aas, K., 1984. Antigens in food. Nutrition reviews, 42(3), pp.85-91.
(https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1753-4887.1984.tb02295.x)

Mills, C., 2011. What makes an antigen a food allergen?. Clinical and Translational Allergy, 1(1), pp.1-1.
Boyce JA, Assa’ad A, Burks AW, Jones SM, Sampson HA, Wood RA, et al. Guidelines for the diagnosis and management of food allergy in the United States: report of the NIAID-sponsored expert panel. J. Allergy Clin Immunol 2010;126(6 Suppl):S1–58.

Burks AW, Tang M, Sicherer S, et al. ICON: Food allergy. J Allergy Clin Immunol 2012, 129:906-20

Connors, L., O’Keefe, A., Rosenfield, L. and Kim, H., 2018. Non-IgE-mediated food
hypersensitivity. Allergy, Asthma & Clinical Immunology, 14(2), pp.1-9.

Demoly P, Tanno LK, Akdis CA, Lau S, et al. Global classification and coding of hypersensitivity diseases – An EAACI – WAO survey, strategic paper and review. Allergy 2014, 69:559–70


Heinzerling, L., Mari, A., Bergmann, K.C., Bresciani, M., Burbach, G., Darsow, U., Durham, S., Fokkens, W., Gjomarkaj, M., Haahtela, T. and Bom, A.T., (2013). The skin prick test–European standards. Clinical and translational allergy, 3(1), p.3.

Roerdink EM, Flokstra-de Blok BM, Blok JL, ET AL. Association of food allergy and atopic dermatitis exacerbations. Ann Allergy Asthma Immunol. 2016;116:334-8
Furuta GT, Katzka DA. Eosinophilic Esophagitis. N Engl J Med 2015;373:1640-8.
Yu, W., Freeland, D. M. H. & Nadeau, K. C. (2016). 'Food allergy: immune mechanisms, diagnosis and immunotherapy', Nature Reviews Immunology, 16(12), p. 7

Disclaimer:
The information in this podcast is for information and entertainment purposes only.
I am not a medical professional so I have never and will never give medical advice. You should always speak to a health care provider about your unique health needs. My opinions are entirely my own. I only discuss published literature in this podcast. I am not responsible for any claims related to the procedures, professionals, products or methods discussed in the podcast, and do does not approve or endorse any products, professionals, services or methods that may be referenced to in this podcast.

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Image description: The image is an infographic, with a light green background. There is a cartoon mustard tub, celery stick and different types of nuts at the bottom left corner. At the bottom right corner there is a cartoon image of a glass of wine, milk carton, tofu, shellfish, crustacean, purple fish and one egg. On the top left corner there are three wheat stalks and sesame and lupin seeds as cartoon images. On the top right there is a logo with a green antibody in a white box. The logo has the words Allergies at the top of the antibody, the word with to the centre left of the antibody and the word Ayah to the centre right of the antibody. At the centre top of the infographic there is the words Allergies with Ayah in written in grey. The word episode 2 is written to the centre left of Ayah’s face. In the centre of the image there is a cartoon character depiction of Ayah. Ayah has brown long hair and is smiling. Ayah’s hand is together in two fists and she is wearing a purple top.