A ganglion cyst is a tumor or swelling on top of a joint or the covering of a tendon that looks like a sac of liquid (cyst). Inside the cyst is a thick, sticky, clear, jellylike material. Depending on the size, cysts may feel firm or spongy. One large cyst or many smaller ones may develop. Multiple small cysts can give the appearance of more than one cyst, but a common stalk within the deeper tissue usually connects them. This type of cyst is not harmful and accounts for about half of all soft tissue tumors of the hand.

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