Vaping, or electronic cigarette use, is becoming increasingly popular, especially among youth and young adults. While it is perceived as safer than tobacco cigarettes, the exact composition of the liquids used in e-cigarettes is not publicly known, making it difficult to predict the health effects. E-cigarette contents include nicotine, flavors, chemical additives, and a solvent. Studies have shown that vaping can have negative effects on cardiovascular health, such as higher arterial stiffness, impaired endothelial function, and increased blood pressure. However, clinical studies were inconclusive, and long-term trials were not available. It is also unclear if e-cigarettes can be effectively used for smoking cessation. We reviewed the contents of the vape, the latest literature, and the statement from the American heart association on electronic cigarettes, and here are the facts.