"Let's Clean Up the Ghetto" is a song released in 1977 by Philadelphia International Records, a soul music label based in Philadelphia, Pennsylvania. The song features vocals from a collective of artists associated with the label, including The Philadelphia International All-Stars. Some of the prominent artists who contributed vocals to the song include:

• Teddy Pendergrass
• Lou Rawls
• Archie Bell
• Dee Dee Sharp Gamble
• Billy Paul
• Harold Melvin & the Blue Notes
• The O'Jays

These artists, among others, came together to perform the song as part of a collaborative effort to raise awareness about the need to address urban blight and poverty in inner-city neighborhoods. "Let's Clean Up the Ghetto" was not only a hit song but also served as a call to action for social change.