Mononucleosis, commonly known as mono, is a viral infection primarily caused by the Epstein-Barr virus (EBV). This article delves into the various aspects of mono, including its symptoms such as fatigue, fever, sore throat, and swollen lymph nodes, as well as less common manifestations like swollen liver or spleen. It outlines the diagnostic process, including medical history, physical exams, and specific tests like the Monospot test. Management strategies emphasize rest, hydration, and over-the-counter medications, along with advice on when to seek medical help. The article also covers prevention methods and the impact of mono on daily life, offering coping strategies and highlighting the importance of awareness and proper care.